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Others expressed concerns that getting an HPV vaccine may lead teenage girls to think it may be safer to have casual sex, although a subsequent study found there is no evidence to suggest the vaccines — Glaxo Smith Kline sells another called Cervarix — leads to risky sexual behavior.
From the start, some parents objected to the cost of the treatment, which requires three shots, costing a total of about 0.
We should note that the study was funded by Merck, which sells the Gardasil HPV vaccine, and that Brewer has received HPV vaccine-related grants from or served on paid advisory boards for Merck.
Interestingly, the study also found 32 percent of parents felt the vaccines are promoted to make money for drug companies, and only 40 percent believed the vaccines are effective in preventing cervical cancer.
Only New Jersey has such a bill pending, while legislation died recently in Hawaii and Maryland, according to the National Conference of State Legislatures.
“It would be hard for lawmakers to enact a policy that has 21 percent support,” Brewer acknowledged.
HPV 16 and HPV 18 are responsible for about 70 percent of invasive cervical cancers and for a larger majority of the HPV-related cancers at other sites [1,2].
Worldwide, about 500,000 cervical cancers annually and about 100,000 cancers at other sites, including vulva and vagina, anus, penis, and oropharynx, are attributable to genital tract HPV .
Even before regulators approved Gardasil, Merck tried to persuade lawmakers to require school districts to make vaccination mandatory.
The effort failed and created lingering distrust of the company, which only two years earlier was ensnared in scandal over its withdrawal of the Vioxx painkiller amid controversy over the extent to which side effect data about cardiovascular risks was properly disclosed.
HPV 6 and HPV 11 account for over 90 percent of genital warts, which are very common, with millions of cases annually worldwide, and for nearly 100 percent of a rare disease, recurrent respiratory papillomatosis of juvenile or adult onset. Cervarix, from Glaxo Smith Kline, is a bivalent vaccine designed to prevent infections with the oncogenic HPV types 16 and 18 .
A second HPV vaccine, Cervarix, is expected to be available in the U. Both vaccines have been shown to be well tolerated, safe, and highly immunogenic in clinical trials [1-3].
Most of all, the vaccines have been plagued by numerous reports of side effects.